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Publications


2017
Liquid PMMA: A High Resolution Polymethylmethacrylate Negative Photoresist as Enabling Material for Direct Printing of Microfluidic Chips [in press].
Kotz, F.; Arnold, K.; Wagner, S.; Bauer, W.; Keller, N.; Nargang, T. M.; Helmer, D.; Rapp, B. E.
2017. Advanced engineering materials. doi:10.1002/adem.201700699
Suspended Liquid Subtractive Lithography: One-step generation of 3D channel geometries in viscous curable polymer matrices.
Helmer, D.; Voigt, A.; Wagner, S.; Keller, N.; Sachsenheimer, K.; Kotz, F.; Nargang, T. M.; Rapp, B. E.
2017. Scientific reports, 7 (1), 7387. doi:10.1038/s41598-017-07630-w
Polymer Structures on Surface Acoustic Wave Biosensors.
Ritter, F.; Hedrich, J.; Deck, M.; Ludwig, F.; Shakirov, D.; Rapp, B. E.; Länge, K.
2017. Procedia Technology, 27, 35–36. doi:10.1016/j.protcy.2017.04.017
An Analytical Solution to Neumann-Type Mixed Boundary Poiseuille Microfluidic Flow in Rectangular Channel Cross-Sections (Slip/No-Slip) including a Numerical Technique to Derive It.
Richter, C.; Kotz, F.; Keller, N.; Nargang, T. M.; Sachsenheimer, K.; Helmer, D.; Rapp, B. E.
2017. Journal of biomedical science and engineering, 10 (05), 205–218. doi:10.4236/jbise.2017.105016
Three-dimensional printing of transparent fused silica glass.
Kotz, F.; Arnold, K.; Bauer, W.; Schild, D.; Keller, N.; Sachsenheimer, K.; Nargang, T. M.; Richter, C.; Helmer, D.; Rapp, B. E.
2017. Nature <London>, 544 (7650), 337–339. doi:10.1038/nature22061
2016
An individual addressable and latchable actuator array for microfluidic systems.
Richter, C.; Sachsenheimer, K.; Keller, N.; Nargang, T. M.; Helmer, D.; Kotz, F.; Rapp, B. E.
2016. Microfluidics and nanofluidics, 20 (9), 130. doi:10.1007/s10404-016-1793-3
Numerics made easy: solving the Navier–Stokes equation for arbitrary channel cross-sections using Microsoft Excel.
Richter, C.; Kotz, F.; Giselbrecht, S.; Helmer, D.; Rapp, B. E.
2016. Biomedical microdevices, 18 (3), 18:52. doi:10.1007/s10544-016-0070-2
Liquid Glass: A Facile Soft Replication Method for Structuring Glass.
Kotz, F.; Plewa, K.; Bauer, W.; Schneider, N.; Keller, N.; Nargang, T.; Helmer, D.; Sachsenheimer, K.; Schäfer, M.; Worgull, M.; Greiner, C.; Richter, C.; Rapp, B.
2016. Advanced materials, 28 (23), 4646-4650. doi:10.1002/adma.201506089
Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC.
Keller, N.; Nargang, T. M.; Runck, M.; Kotz, F.; Striegel, A.; Sachsenheimer, K.; Klemm, D.; Länge, K.; Worgull, M.; Richter, C.; Helmer, D.; Rapp, B. E.
2016. Lab on a chip, 16 (9), 1561-1564. doi:10.1039/C5LC01498K
Localized protein immobilization on microstructured polymeric surfaces for diagnostic applications.
Steidle, N. E.; Hahn, T.; Bader, C.; Ahrens, R.; Rapp, B. E.; Guber, A. E.; Länge, K.
2016. Microfluidics and nanofluidics, 20 (2), 1-11. doi:10.1007/s10404-015-1696-8
2015
Synthetic enzyme supercomplexes: co-immobilization of enzyme cascades (vol 7, pg 4030, 2015).
Kazenwadel, F.; Franzreb, M.; Rapp, B. E.
2015. Analytical methods, 7 (18), 7924. doi:10.1039/c5ay90065d
Quantification of the influence of endotoxins on the mechanics of adult and neonatal red blood cells.
Ito, H.; Kuss, N.; Rapp, B. E.; Ichikawa, M.; Gutsmann, T.; Brandenburg, K.; Pöschl, J. M. B.; Tanaka, M.
2015. Journal of Physical Chemistry B, 119 (25), 7837-7845. doi:10.1021/acs.jpcb.5b01544
Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8:CXCR1 complex.
Helmer, D.; Rink, I.; Dalton, J. A. R.; Brahm, K.; Jöst, M.; Nargang, T. M.; Blum, W.; Wadhwani, P.; Brenner-Weiss, G.; Rapp, B. E.; Giraldo, J.; Schmitz, K.
2015. RSC Advances, 5, 25657-25668. doi:10.1039/C4RA13749C
Synthetic enzyme supercomplexes: Co-immobilization of enzyme cascades.
Kazenwadel, F.; Franzreb, M.; Rapp, B. E.
2015. Analytical Methods, 7 (10), 4030-4037. doi:10.1039/c5ay00453e
Polysiloxane layers created by sol-gel and photochemistry: Ideal surfaces for rapid, low-cost and high-strength bonding of epoxy components to polydimethylsiloxane.
Wilhelm, E.; Deshpande, K.; Kotz, F.; Schild, D.; Keller, N.; Heissler, S.; Sachsenheimer, K.; Länge, K.; Neumann, C.; Rapp, B. E.
2015. Lab on a Chip, 15 (7), 1772-1782. doi:10.1039/c4lc01440e
Acoustic biosensors coated with phosphorylcholine groups for label-free detection of human C-Reactive Protein in serum.
Pomowski, A.; Baricham, C.; Rapp, B. E.; Matern, A.; Länge, K.
2015. IEEE sensors journal, 15 (8), 4388-4392. doi:10.1109/JSEN.2015.2419278
Bioinspired air-retaining nanofur for drag reduction.
Kavalenka, M. N.; Vüllers, F.; Lischker, S.; Zeiger, C.; Hopf, A.; Röhrig, M.; Rapp, B. E.; Worgull, M.; Hölscher, H.
2015. ACS applied materials & interfaces, 7, 10651-10655. doi:10.1021/acsami.5b01772
2014
Liquid polystyrene: a room-temperature photocurable soft lithography compatible pour-and-cure-type polystyrene.
Nargang, T. M.; Brockmann, L.; Nikolov, P. M.; Schild, D.; Helmer, D.; Keller, N.; Sachsenheimer, K.; Wilhelm, E.; Pires, L.; Dirschka, M.; Kolew, A.; Schneider, M.; Worgull, M.; Giselbrecht, S.; Neumann, C.; Rapp, B. E.
2014. Lab on a chip, 14 (15), 2698-2708. doi:10.1039/C4LC00045E
Advances in DNA-directed immobilization.
Meyer, R.; Giselbrecht, S.; Rapp, B. E.; Hirtz, M.; Niemeyer, C. M.
2014. Current Opinion in Chemical Biology, 18, 8-15. doi:10.1016/j.cbpa.2013.10.023
Biofunctional micropatterning of thermoformed 3D substrates.
Waterkotte, B.; Bally, F.; Nikolov, P. M.; Waldbaur, A.; Rapp, B. E.; Truckenmüller, R.; Lahann, J.; Schmitz, K.; Giselbrecht, S.
2014. Advanced Functional Materials, 24, 442-450. doi:10.1002/adfm.201301093
2013
Rapid bonding of polydimethylsiloxane to stereolithographically manufactured epoxy components using a photogenerated intermediary layer.
Wilhelm, E.; Neumann, C.; Sachsenheimer, K.; Schmitt, T.; Länge, K.; Rapp, B. E.
2013. Lab on a Chip - Miniaturisation for Chemistry and Biology, 13 (12), 2268-2271. doi:10.1039/c3lc50341k
Connecting microfluidic chips using a chemically inert, reversible, multichannel chip-to-world-interface.
Wilhelm, E.; Neumann, C.; Duttenhofer, T.; Pires, L.; Rapp, B. E.
2013. Lab on a Chip - Miniaturisation for Chemistry and Biology, 13 (22), 4343-4351. doi:10.1039/c3lc50861g
Microfluidics on liquid handling stations (μF-on-LHS): an industry compatible chip interface between microfluidics and automated liquid handling stations.
Waldbaur, A.; Kittelmann, J.; Radtke, C. P.; Hubbuch, J.; Rapp, B. E.
2013. Lab on a Chip - Miniaturisation for Chemistry and Biology, 13 (12), 2337-2343. doi:10.1039/c3lc00042g
Computer-aided microfluidics (CAMF): From digital 3D-CAD models to physical structures within a day.
Waldbaur, A.; Carneiro, B.; Hettich, P.; Wilhelm, E.; Rapp, B. E.
2013. Microfluidics and Nanofluidics, 15 (5), 625-635. doi:10.1007/s10404-013-1177-x
Online monitoring of biofilm growth and activity using a combined multi-channel impedimetric and amperometric sensor.
Pires, L.; Sachsenheimer, K.; Kleintschek, T.; Waldbaur, A.; Schwartz, T.; Rapp, B. E.
2013. Biosensors and bioelectronics, 47, 157-163. doi:10.1016/j.bios.2013.03.015
The chemistry of cyborgs interfacing technical devices with organisms.
Giselbrecht, S.; Rapp, B. E.; Niemeyer, C. M.
2013. Angewandte Chemie - International Edition, 52, 13942-13957. doi:10.1002/anie.201307495
Design and characterization of a platform for thermal actuation of up to 588 microfluidic valves.
Neumann, C.; Voigt, A.; Pires, L.; Rapp, B. E.
2013. Microfluidics and Nanofluidics, 14 (1-2), 177-186. doi:10.1007/s10404-012-1036-1
2011
Hot embossing of high performance polymers.
Worgull, M.; Kolew, A.; Heilig, M.; Schneider, M.; Dinglreiter, H.; Rapp, B. E.
2011. Microsystem Technologies, 17 (4), 585-592. doi:10.1007/s00542-010-1155-0
Let there be chip - towards rapid prototyping of microfluidic devices: one-step manufacturing processes.
Waldbaur, A.; Rapp, H.; Länge, K.; Rapp, B. E.
2011. Analytical Methods, 3 (12), 2681-2716. doi:10.1039/C1AY05253E
2010
Biosensor packaging - adaptation of the surface modification procedure.
Gruhl, F. J.; Rapp, B. E.; Rapp, M.; Länge, K.
2010. Procedia Engineering, 5, 363-366. doi:10.1016/j.proeng.2010.09.123
Synthesis and application of photo curable perfluoropolyethers as new material for microfluidics.
Hannig, C.; Dirschka, M.; Länge, K.; Neumaier, S.; Rapp, B. E.
2010. Procedia Engineering, 5, 866-69. doi:10.1016/j.proeng.2010.09.246
Biosensors with label-free detection designed for diagnostic applications.
Rapp, B. E.; Gruhl, F. J.; Länge, K.
2010. Analytical and Bioanalytical Chemistry, 398, 2403-12. doi:10.1007/s00216-010-3906-2
Hot punching on an 8 inch substrate as an alternative technology to produce holes on a large scale.
Rapp, B. E.; Schneider, M.; Worgull, M.
2010. Microsystem Technologies, 16, 1201-06. doi:10.1007/s00542-009-0943-x
2008
Surface acoustic wave biosensors: a review.
Länge, K.; Rapp, B. E.; Rapp, M.
2008. Analytical and Bioanalytical Chemistry, 391, 1509-19. doi:10.1007/s00216-008-1911-5
2007
Surface acoustic wave biosensors for biomedical applications.
Rapp, B.; Länge, K.; Rapp, M.; Guber, A.
2007. Biomedizinische Technik, BMT 2007 : 41.Jahrestagung der Deutschen Gesellschaft für (DGBMT), Aachen, 26.-29.September 2007, Ergänzungsbd.auf CD-ROM, 52
Polymer coating behavior of Rayleigh-SAW resonators with gold electrode structure for gas sensor applications.
Avramov, I. D.; Länge, K.; Rupp, S.; Rapp, B.; Rapp, M.
2007. IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control, 54, 157-66. doi:10.1109/TUFFC.2007.221