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Alexander Nesterov-Müller

Prof. Dr. Alexander Nesterov-Müller

Molecular Search Engines
Phone: +49 721 608-29253
alexander nesterov-muellerIma2∂kit edu

Karlsruhe Institute of Technology
Institute of Microstructure Technology
Hermann-von-Helmholtz-Platz 1
76344 Eggenstein-Leopoldshafen


Like the Google search engine reacts on your requests, the Molecular Search Engines will experimentally provide you information about relevant molecules or molecule-based processes. Molecular Search Engines copy evolutionary principle: they use the diversity of the combinatorial molecules and the selection of binding events in the array format. Generation of super high density molecular arrays is the main goal of our research. To develop the Molecular Search Engines, we use our ERC-grant awarded approach of combinatorial monomer patterning with “smart” particles. We also develop high throughput screening applications in life and material sciences.



1998    Diploma Physicist with Honor from Lomonosov Moscow State University

2006    Dr. rer.nat. in Physics from University of Heidelberg

2008    Interdisciplinary Habilitation on Molecular High Density Arrays at University of Heidelberg/ German Cancer Research Center

2010    Assistant Professor (Privatdozent) at Karlsruhe Institute of Technology, Institute of Microstructure Technology

2015    Associate Professor (apl. Professor) at Karlsruhe Institute of Technology, Faculty of Mechanical Engineering



Awards: ERC Starting Grant (2011), Helmholtz Association Price (2011), HRJRG-Grant (2011), ERC Proof-of-Principle Grant (2015)



Selected Publications*:

Foertsch T C, Davis A T, Popov R, von Bojničić-Kninski C., Held F E, Tsogoeva S B, Loeffler F F, Nesterov-Mueller A (2019) Spatial Modes of Laser-Induced Mass Transfer in Micro-Gaps. Applied Sciences 9 (7), 1303

Palermo A, Thelen R, Weber L K, Foertsch T, Rentschler S., Hackert V., Syurik J., Nesterov-Mueller A (2019) Vertical Scanning Interferometry for Label-Free Detection of Peptide-Antibody Interactions, High-Throughput 8 (2).

Palermo A & Nesterov-Mueller A (2019) Serological Number for Characterization of Circulating Antibodies. Int J Mol Sci 20, doi:10.3390/ijms20030604.

Bojnicic-Kninski C, Bykovskaya V, Maerkle F, Popov R, Palermo A, Mattes D S, Weber L K, Ridder B, Foertsch T C, Loeffler F F, Breitling F, and Nesterov-Mueller A (2016) Selective Functionalization of Microstructured Surfaces by Laser-Assisted Particle Transfer Adv Funct. Materials, DOI: 10.1002/adfm.201603299

Loeffler F F, Foertsch T C, Popov R, Mattes D S, Schlageter M, Sedlmayr M, Ridder B, Dang F-X, von Bojničić-Kninski C, Weber LK, Fischer A,Greifenstein J, Bykovskaya V, Buliev I, Bischoff F R, Hahn L, Meier M A R, Bräse S, Powell A K, BalabanT S, Breitling F, Nesterov-Mueller A (2016) High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in matrix material. Nature Communications, DOI: 10.1038/NCOMMS11844

Nesterov-Müller A (2016) Erfolgreicher Grenzgang : Bunsen und Kirchhoff: Entdeckung der Spektralanalyse, Physik in unserer Zeit, 47: 233–237, DOI: 10.1002/piuz.201601440

Maerkle F, Loeffler F F, Schillo S, Foertsch T, Muenster B, Striffler J, Schirwitz C, Bischoff F R, Breitling F, Nesterov-Mueller A (2014) High-Density Peptide Arrays with Combinatorial Laser Fusing, Advanced Materials, V. 26: 3730–3734

Nesterov-Mueller A, Märkle F, Förtsch T, Schillo S, Hahn L, Bykovskaya V, Sedlmayr M, Soehindrijo M, Münster B, Striffler J, Bischoff F R, Breitling F, Loeffler F F (2014) Particle-based microarrays of oligonucleotides and oligopeptides, New and Old Technologies for Generation of Microarrays, Microarrays, 3, 245-262

Loffler F, Cheng YC, Fortsch T, Dorsam E, Bischoff R, Breitling F and Nesterov-Mueller A  (2011) Biofunctional Xerography, InTech,  in  Biotechnology of Biopolymers ISBN 978-953-307-179-4, p 275-290

Nesterov A, König K, Felgenhauer T, Lindenstruth V, Trunk U, Fernandez S, Hausmann M., Bischoff F R, Stadler V und Breitling F. (2008) Precise selective deposition of microparticles on electrodes of microelectronic chips. Rev. Scientific Instruments, 79, 035106.

Beyer M, Nesterov A (shared fist author), Block I, König K, Felgenhauer T, Fernandez S, Leibe K, Torralba G, Hausmann M, Trunk U, Lindenstruth V, Bischoff FR, Stadler V und Breitling F. (2007) Combinatorial synthesis of peptide arrays onto a computer chip’s surface. Science 318, 1888.

Nesterov-Müller A (2006) Ortsgenaue Ablagerung von Aminosäurepartikeln für die kombinatorische Synthese von Peptidarrays auf einen Chip, Dissertation, Universität Heidelberg.

Nesterov A, Paasch G, Scheinert S und Lindner T (2002) Simulation study of the influence of polymer modified anodes on organic LED performance. Synthetic Metals 130, 165-175.

Nesterov A, Troppenz U. (2003) A plane wave boundary method for analysis of bent optical waveguides, J. Lightwave Technology, 21, 2434-2437.

Nesterov AV, Niziev VG und Yakunin VP. (1999) Generation of high-power radially polarized beam. J. of Phys. D Appl. Phys. 32, 2871-2875.

Niziev VG and Nesterov AV. (1999) Influence of Beam Polarization on Laser Cutting Efficiency. J. of Phys. D Appl. Phys. 32, 1455-1461.

* My name has changed because of emigration and family reasons. My publications were written under different names: Nesterov AV, Nesterov A, Nesterov-Mueller A