Leona Schmidt-Speicher

M.Sc. Leona Schmidt-Speicher

  • Karlsruhe Institute of Technology
    Institute of Microstructure Technology
    Hermann-von-Helmholtz-Platz 1
    76344 Eggenstein-Leopoldshafen

Leona Schmidt-Speicher received her M.Sc. degree in mechanical engineering in November 2019 from the Karlsruhe Institute of Technology (KIT). During her degrees, she studied and worked at the University of Purdue (USA), wrote her bachelor thesis and worked at Global Advanced Manufacturing Institute (GAMI, China) and studied at the University of Córdoba (Argentina). She specialized in Medical Engineering and Microstructure Technology. After completing her studies, she joined the group “BioMEMS – Biomedizinische Mikrotechnik” of Prof. Dr. A. E. Guber at the Institute of Microstructure Technology (IMT) in the research field of biomedical microtechnology in December 2019. During her Ph.D., she will be working on the development of a modular microfluidic bioreactor for plant cell cultivation within the Dialog-ProTec-Project.

Research topics

  • BioMEMS
  • Microfluidic systems
  • Ultrasonic welding

Research experiences

  • BioMEMS
  • Mechanical bactericidal surfaces on Titanium
  • Fabrication of Micro- and Nanostructures
    • Electron Beam Lithography
    • Deep Reactive Ion Etching (DRIE)
  • Surface Analysis
    • Atomic Force Microscopy (AFM)
    • Vertical Scanning Interferometry (VSI)
Upcoming Lectures at KIT within the Department of Mechanical Engineering
Title Type Semester
Practical course WS
Lecture SS

Supervised students‘ theses

  • Master's thesis: "Optimierung eines mikrofluidischen Chips zur Untersuchung des Wurzelwachstums und Ermittlung der industriellen Fertigungsmöglichkeiten durch eine Unternehmensstudie - Optimization of a Microfluidic Chip for the Analysis of Root Growth and Determination of the Industrial Production Possibilities through a Company Study". 2020. E. Pawlenko.
  • Master's thesis: "Konstruktiver Anschluss von Sensoren an einen mikrofluidischen Bioreaktor sowie deren Testung auf Eignung für die online-Ermittlung der    entsprechenden Parameter - Connection of sensors to a microfluidic bioreactor". 2021. B. Bailer.
  • Master's thesis: "Additive Fertigung und Untersuchung eines Formeinsatzes für PDMS basierte Mikrofluidikchips - Additive Manufacturing and Analysis of a Mold for PDMS   based Microfluidic Chips". 2021. T. Mellert.


Development of a modular microfluidic bioreactor to further research the inter-cellular communication of plant cells and pathogens.
Schmidt-Speicher, L. M.; Supp, L.; Metzger, C.; Ahrens, R.; Nick, P.; Guber, A. E.
2021. MikroSystemTechnik Kongress 2021, VDE e.V., 543–547, VDE Verlag 
Microfluidic integration for electrochemical biosensor applications.
Schmidt-Speicher, L. M.; Länge, K.
2021. Current opinion in electrochemistry, 29, Article: 100755. doi:10.1016/j.coelec.2021.100755
Rapid Prototyping of Moulds for PDMS-based Microfluidic Chips.
Schmidt-Speicher, L. M.; Mellert, T.; Hurtado Rivera, A. C.; Länge, K.; Ahrens, R.; Guber, A. E.
2021. Current directions in biomedical engineering, 7 (2), 255–259. doi:10.1515/cdbme-2021-2065Full textFull text of the publication as PDF document
A modular microfluidic bioreactor to investigate plant cell–cell interactions.
Finkbeiner, T.; Manz, C.; Raorane, M. L.; Metzger, C.; Schmidt-Speicher, L.; Shen, N.; Ahrens, R.; Maisch, J.; Nick, P.; Guber, A. E.
2021. Protoplasma. doi:10.1007/s00709-021-01650-0Full textFull text of the publication as PDF document