(Dr. Vlad Badilita, Prof. Jan G. Korvink, )
At SPA Lab, we employ MEMS fabrication techniques to develop advanced miniaturised detectors for nuclear magnetic resonance (NMR) spectroscopy of sub-microliter samples. The so-called MACS detectors are being used in the magic angle spinning (MAS) configuration, the main difference being that here, both the detector and the sample rotate rapidly in the magnetic field and the signal is transmitted via inductive coupling between the MACS coil and the static coil.
Combining microfluidic devices with nuclear magnetic resonance (NMR) has the potential of unlocking their vast sample handling and processing operation space for use with the powerful analytics provided by NMR. One particularly challenging class of integrated functional elements from the perspective of NMR are conductive structures. Metallic electrodes could be used for electrochemical sample interaction for example, yet they can cause severe NMR spectral and SNR degradation.
In a hybrid micromachined contactless suspension prototype, which combines electromagnetic inductive and electrostatic actuation, we have demonstrated an increase in operational capabilities such as dynamical adjustment of stiffness components, linear and angular positioning, as well as bistable actuation of the levitated proof mass.
(Prof. Jan G. Korvink, ,
Hyperspectral imaging (HSI) is a technology which combines 2D spatial imaging and spectroscopy to provide detailed information about the composition of a target. Hyperspectral imaging enables the acquisition of spatially-resolved spectral information by acquiring a spectrum for each pixel in an image using many contiguous narrow spectral bands. The acquired spatial and spectral information forms a 3D data set, which is often referred to as the “hyperspectral cube”.
(Prof. Jan G. Korvink, )
Optical tweezers, is a single-molecule manipulation technique that can exert forces on particles (ranging from nanometers to microns) and at the same time measuring the displacement with sub-nanometer accuracy. Optical tweezing is simply the concentration of optical power in a small area. This concentration of power gives the ability to affect the motion of particles.