X-ray Micro-Technology (XMT)

Prof. Dr. Venera Weinhardt [Contact]

Welcome

...to the Weinhardt lab! X-ray imaging is a powerful technology that has been extensively used in medical diagnosis and industrial non-destructive inspection. We are working in this exciting, fast-developing field, with expertise at the interface of micro- and nanofabrication, optical technologies, and machine learning.

Our department works on technological developments in micro- and nano-X-ray imaging across multiple structural scales, focusing on laboratory solutions accessible to the broader research community. We develop novel sample preparation technologies, imaging methods, and algorithms for quantitative analysis, including AI-driven image segmentation methods. For our work, we have established a set of tools and resources available only within our department. Our research contributes to the research program 3: "Materials Systems Engineering" (MSE), Topic 5: "Materials Information Discovery", Link to MSE website.

 

Research Groups

Cross-sectional multimodal X-ray image of a small organism with green-highlighted regions. IMT-XMT
Multimodal X-ray Imagıng
High-mlication microfabricated patterned structure with parallel comb-like layers, 500 µm scale.
Applied X-ray Imaging
Grayscale-styled 3D cell showing red fibrous network with blue nuclei.
Correlative X-ray Imaging
Two cellular images connected by a small AI icon; left is a grayscale cell, right is a colorful 3D organ model.
AI assisted Imaging
 

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News

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X-ray science, on the Girl’s Day at IMT

 

It was a great pleasure to welcome 24 curious and creative young girls to our department at IMT as part of this year’s Girls’ Day. We were showcasing the fascinating world of X-ray imaging, where girls could transform science into art using simple everyday objects. X-rays can be literally insightful! A big thank you to my team and to 3DMM2O for making this event so inspiring. We’re excited to see the next generation of scientists take their first steps into research.

Chest CT images in three window settings (axial slices) showing a rounded mass.
New Open-Source Framework Advances Multicontrast X-ray Imaging

IMT researchers at KIT published "SHI: a framework for spatial harmonic imaging" in Scientific Reports. SHI is a modular Python framework for multicontrast X-ray imaging using periodic modulators (e.g., Hartmann masks). It automates acquisition, higher-order-harmonic retrieval, and CT preprocessing, extracting absorption, refraction, and scattering signals from a single exposure. Robust to large focal spots and optical imperfections, it reveals internal structures across a range of contrasts with fewer projections, reducing dose.

Read the full manuscript here